Found 14 matching trials
A Study of Chenodeoxycholic Acid (CDCA) in Newly Diagnosed Participants With Cerebrotendinous Xanthomatosis (CTX)
PHASE3This study is designed to demonstrate the beneficial effect of CDCA in the ...
Location
Sheba Medical Center
Effect of Bile Acids on GLP-1 Secretion
NAThe purpose of this study is to describe the physiological, pathophysiologi...
Location
Diabetes Research Division, Department of Internal Medicine, Gentofte Hospital, University of Copenhagen
Phase 3 Study of Obeticholic Acid in Patients With Primary Biliary Cirrhosis
PHASE3The main objectives of the study were to assess the effects of Obeticholic ...
Location
UC Davis Medical Center
Study to Evaluate Patients With Cerebrotendinous Xanthomatosis (RESTORE)
PHASE3The study is made up of two cohorts: a randomized double-blind crossover (p...
Location
Travere Investigational Site
Study of INT-747 as Monotherapy in Participants With Primary Biliary Cirrhosis (PBC)
PHASE2The primary hypothesis was that obeticholic acid (OCA) will cause a reducti...
Effects of FXR Activation on Hepatic Lipid and Glucose Metabolism
EARLY_PHASE1The purpose of this study is to determine whether chenodeoxycholic acid dec...
Location
University Hospital Basel
Effects of Bile Acids on GLP-1 Secretion After Roux-en-Y Gastric Bypass
PHASE4The purpose of this study is to examine the effects of bile acids on GLP-1 ...
Location
Hvidovre University Hospital
Impact of Metformin and Polysorbate 80 on Drug Absorption and Disposition
PHASE4The study employs two-sub-studies that share a common placebo arm.
The obj...
Location
University of Maryland
Cheno Effect on Transit in Health and IBS-C
PHASE2The study hypothesis is that the naturally occurring bile acid, chenodeoxyc...
Intravenous Infusion of CAP-1002 in Patients With COVID-19
PHASE2This is a randomized, double-blind, placebo-controlled, Pilot, Phase 2 Expl...
Location
Cedars-Sinai Medical Center